5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in fat cell metabolism and energy regulation. By blocking NNMT, it may boost NAD+ levels, enhance metabolic rate, and activate the “longevity gene” SIRT1. Research suggests potential benefits for reducing fat cell size, supporting weight management, and promoting metabolic, cardiovascular, and neuroprotective health.